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| Phân tích đa dạng vi khuẩn chí dựa trên mạng lưới× | Phylogenetic Analysis× | |
|---|---|---|
| Lĩnh vực | Tin sinh học | Tin sinh học |
| Họ | Process / pipeline | Process / pipeline |
| Năm ra đời≠ | 2012 | 1960s-1981 (distance trees ~1967; ML framework formalised 1981) |
| Người khởi xướng≠ | Faust, Raes, Friedman, Alm and colleagues | Joseph Felsenstein (maximum likelihood framework); Walter Fitch and Emanuel Margoliash (distance methods) |
| Loại≠ | Integrative bioinformatics pipeline | Computational inference method |
| Công trình gốc≠ | Friedman, J., & Alm, E. J. (2012). Inferring correlation networks from genomic survey data. PLoS Computational Biology, 8(9), e1002687. DOI ↗ | Felsenstein, J. (2004). Inferring Phylogenies. Sinauer Associates. ISBN: 978-0878931774 |
| Tên gọi khác | microbial co-occurrence network analysis, microbiome network ecology, ecological network-based diversity, NBMDA | molecular phylogenetics, phylogenetic inference, evolutionary tree reconstruction, phylogenomics |
| Liên quan | 5 | 5 |
| Tóm tắt≠ | Network-based microbiome diversity analysis integrates graph-theoretic co-occurrence network inference with classical alpha- and beta-diversity metrics to characterize the structural organization of microbial communities. Rather than treating taxa as independent entities, the method models pairwise microbial associations as edges in a network, enabling identification of keystone taxa, community modules, and ecological interaction patterns that simple diversity indices cannot detect. | Phylogenetic analysis reconstructs the evolutionary history of organisms, genes, or proteins by comparing molecular sequence data and estimating the branching tree that best explains observed similarities and differences. Rooted in the work of Felsenstein and colleagues from the 1960s onward, it is a cornerstone technique in evolutionary biology, microbiology, epidemiology, and comparative genomics, supporting tasks from tracing viral outbreak origins to classifying novel species. |
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