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Sắc ký ion×Đo điện lượng×
Lĩnh vựcHóa phân tíchHóa phân tích
HọProcess / pipelineProcess / pipeline
Năm ra đời19751945
Người khởi xướngHamish SmallJames Lingane
Loạiseparation and analysis techniqueelectrochemical titration
Công trình gốcSmall, H., Stevens, T. S., & Bauman, W. C. (1989). Novel ion exchange chromatographic method using conductometric detection. Analytical Chemistry, 47(11), 1801–1809. DOI ↗Lingane, J. J. (1974). Electroanalytical Chemistry (2nd ed.). Interscience Publishers. ISBN: 978-0486409023
Tên gọi khácIC, ion-exchange chromatography, IECcoulometric titration, electrochemical coulometry, amperes titration
Liên quan55
Tóm tắtIon chromatography is a liquid chromatography method that separates ions and polar molecules based on their relative affinity for the ion exchange resin in the column. Developed by Hamish Small in 1975, it combines ion-exchange separation with conductivity detection, enabling rapid, sensitive, and simultaneous determination of multiple ions in a single analysis. Ion chromatography has become an indispensable tool for monitoring environmental pollutants, analyzing food and pharmaceutical products, and studying complex ionic mixtures.Coulometry is an electrochemical analytical method that determines the concentration of an analyte by measuring the total electric charge (in coulombs) required to oxidize or reduce the analyte completely at an electrode. Developed by James J. Lingane in the 1940s, coulometry is highly accurate because it is based on fundamental constants (Faraday's law) and does not require external standards or calibration curves. This method is particularly valuable for trace analysis, water determination, and analysis of reactive species.
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