So sánh phương pháp

	Thiết kế Lập phương Trung tâm Lai ghép	Thiết kế Box-Behnken
Lĩnh vực	Thiết kế thí nghiệm	Thiết kế thí nghiệm
Họ	Process / pipeline	Process / pipeline
Năm ra đời	1976	1960
Người khởi xướng	K. G. Roquemore	George E. P. Box and Donald W. Behnken
Loại	Response surface experimental design	Response surface design (incomplete three-level factorial)
Công trình gốc	Roquemore, K. G. (1976). Hybrid designs for quadratic response surfaces. Technometrics, 18(4), 419–423.	Box, G. E. P., & Behnken, D. W. (1960). Some new three level designs for the study of quantitative variables. Technometrics, 2(4), 455–475.
Tên gọi khác	Hybrid CCD, HCCD, modified central composite design, hybrid RSM design	BBD, Box-Behnken, Box-Behnken RSM design, three-level incomplete factorial design
Liên quan	3	3
Tóm tắt	Hybrid Central Composite Design (Hybrid CCD) is a class of response surface designs introduced by Roquemore (1976) that combines the structural properties of classical central composite designs with modified or reduced point configurations to achieve rotatability or near-rotatability with fewer experimental runs than a standard CCD, making it especially practical when the number of factors is three to six and experimental resources are limited.	The Box-Behnken design (BBD) is an efficient response surface methodology design that fits a full second-order polynomial model using three levels of each factor. Introduced by Box and Behnken in 1960, it places experimental points at the midpoints of the edges of a hypercube and at the center, avoiding the corner points where all factors are simultaneously at their extreme levels. This structure makes BBD particularly attractive when extreme-level combinations are physically impossible, costly, or unsafe to test.