So sánh phương pháp

	GPC/SEC	Phân tích Cơ động Lực học	Kéo sợi tĩnh điện
Lĩnh vực	Vật liệu sinh học	Vật liệu sinh học	Vật liệu sinh học
Họ	Process / pipeline	Process / pipeline	Process / pipeline
Năm ra đời	1962	1960	1934
Người khởi xướng	Moore and Debye	Ferry and Schwarzl	Anton Formhals
Loại	Chromatographic analysis	Rheological characterization	Fiber fabrication process
Công trình gốc	Striegel, A. M., Yau, W. W., Kirkland, J. J., & Bly, D. D. (2009). Modern size-exclusion liquid chromatography: practice and theory. John Wiley & Sons.	Menard, K. P. (2008). Dynamic mechanical analysis: a practical introduction (2nd ed.). CRC Press.	Formhals, A. (1934). Process and apparatus for preparing artificial threads. U.S. Patent 1,975,504.
Tên gọi khác	size exclusion chromatography, molecular weight determination, polymer characterization	DMA, rheological analysis, viscoelastic testing	electrospun fiber production, electrostatic fiber spinning
Liên quan	3	3	3
Tóm tắt	Gel permeation chromatography (GPC), also known as size exclusion chromatography (SEC), is an analytical technique for determining the molecular weight distribution (MWD) and average molecular weight (Mw, Mn) of polymers. The method separates polymer molecules by their hydrodynamic size as they pass through a porous chromatography column: larger molecules elute first (excluded from pores), while smaller molecules are retained longer. Developed by Moore and colleagues in the 1960s, GPC/SEC is now the standard method for characterizing polymer chains, assessing polymer degradation over time, and verifying batch consistency in biomaterial production.	Dynamic mechanical analysis (DMA) measures the viscoelastic properties of materials—their elastic stiffness and viscous damping—by applying a sinusoidal stress or strain and measuring the phase lag and amplitude of the material's response. Developed from rheology principles in the 1960s and formalized by Ferry, Schwarzl, and others, DMA provides quantitative measures of how polymeric biomaterials respond to time-dependent and frequency-dependent mechanical stimuli. Key outputs include the storage modulus (elastic component), loss modulus (viscous component), and loss tangent (tan δ), which together characterize the material's mechanical behavior across temperature and frequency ranges.	Electrospinning is an electrostatic fiber fabrication process that uses a high electric field to draw polymer solutions or melts into nanoscale fibers. Developed by Anton Formhals in the 1930s and refined by researchers including Darrell Reneker in the 1990s, the technique has become foundational to biomaterials engineering, enabling the creation of porous scaffolds for tissue engineering and drug delivery systems.