So sánh phương pháp

	Phân tích liều-đáp ứng	Nghiên cứu sinh thái
Lĩnh vực	Dịch tễ học	Dịch tễ học
Họ	Process / pipeline	Process / pipeline
Năm ra đời	Conceptual roots 16th century; modern epidemiological application mid-20th century	19th century (Snow 1854); formalised mid-20th century
Người khởi xướng	Paracelsus (conceptual foundation); formalized by John Snow and later Bradford Hill	Various; foundational work by John Snow (1854) and systematised in modern form by Brian MacMahon and colleagues
Loại	Quantitative analytical method	Observational epidemiological study
Công trình gốc	Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641	Morgenstern, H. (1995). Ecologic studies in epidemiology: concepts, principles, and methods. Annual Review of Public Health, 16(1), 61–81.
Tên gọi khác	exposure-response analysis, concentration-response modeling, dose-response modeling, DRA	aggregate study, correlational study, ecological correlation study, population-level study
Liên quan	4	5
Tóm tắt	Dose-response analysis quantifies the relationship between the magnitude of an exposure (the dose) and the probability or rate of an outcome (the response). It is a core analytical strategy in epidemiology and toxicology, providing evidence that increasing exposure systematically increases — or decreases — the risk of disease. A demonstrated dose-response gradient is one of Bradford Hill's classic criteria supporting causal inference.	An ecological study is an observational epidemiological design in which the unit of analysis is a group or population — a country, region, city, or time period — rather than an individual. Exposures and outcomes are measured as aggregates (rates, proportions, or means) and then correlated across groups to generate or evaluate hypotheses about population-level associations between risk factors and disease.