So sánh phương pháp

	Thiết kế thực nghiệm đối tượng đơn chéo nhau	Nghiên cứu đối chứng ngẫu nhiên (RCT)
Lĩnh vực	Thiết kế thí nghiệm	Thiết kế thí nghiệm
Họ	Process / pipeline	Hypothesis test
Năm ra đời	1970s–1980s (single-case crossover formalized in behavioral research context)	1948
Người khởi xướng	Developed within the single-case research tradition; crossover application formalized by Barlow and Hersen and expanded by Kazdin	James Lind (early precursor, 1747); modern formulation: Austin Bradford Hill & Medical Research Council (1948)
Loại	Experimental single-subject design	Interventional comparative study
Công trình gốc	Kazdin, A. E. (2011). Single-Case Research Designs: Methods for Clinical and Applied Settings (2nd ed.). Oxford University Press. ISBN: 978-0195341881	Schulz, K.F., Altman, D.G., Moher, D., for the CONSORT Group (2010). CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials. BMJ, 340, c332.
Tên gọi khác	crossover SSED, alternating-treatments crossover design, single-case crossover design, N-of-1 crossover design	RCT, randomised controlled trial, clinical trial, Randomize Kontrollü Çalışma (RCT) Tasarımı
Liên quan	4	7
Tóm tắt	The crossover single-subject experimental design (crossover SSED) applies two or more treatment conditions sequentially to the same individual, with a washout or return-to-baseline period between conditions. Because each participant serves as their own control, between-subject variability is eliminated, enabling precise causal inference about treatment effects even with very small samples — often a single participant. This design is widely used in applied behavior analysis, special education, rehabilitation, and clinical psychology.	A randomized controlled trial (RCT) is the gold standard experimental design in clinical and health research, in which participants are randomly allocated to a treatment group or a control group so that the effect of an intervention can be measured with the highest possible degree of internal validity. The modern parallel-group RCT was formalized by Austin Bradford Hill and the Medical Research Council in their landmark streptomycin trial of 1948, and its reporting is governed today by the CONSORT 2010 guidelines (Schulz et al., 2010).