So sánh phương pháp

	Thí nghiệm đa nhánh bắt chéo	Thử nghiệm đối chứng ngẫu nhiên bắt chéo
Lĩnh vực	Thiết kế thí nghiệm	Thiết kế thí nghiệm
Họ	Process / pipeline	Process / pipeline
Năm ra đời	Mid-20th century; multi-arm extensions formalized by 1970s–1980s	1960s (Grizzle 1965 for statistical foundations); widely used in clinical research since the 1970s
Người khởi xướng	Developed from early crossover trial methodology (Williams 1949; Cochran & Cox 1957)	Early formalized by statisticians including Bradford Hill and colleagues in clinical trials; theoretical framework developed by Grizzle (1965) and later Senn (2002)
Loại	Within-subject experimental design with multiple treatment arms	Experimental within-subject design
Công trình gốc	Jones, B., & Kenward, M. G. (2003). Design and Analysis of Cross-Over Trials (2nd ed.). Chapman and Hall/CRC. ISBN: 978-1584883869	Senn, S. (2002). Cross-over Trials in Clinical Research (2nd ed.). Wiley. ISBN: 978-0471496533
Tên gọi khác	multi-arm crossover trial, multi-period multi-treatment crossover, CMAT, multi-treatment crossover experiment	crossover RCT, crossover trial, within-subject RCT, AB/BA crossover design
Liên quan	5	5
Tóm tắt	A crossover multi-arm experiment is a within-subject experimental design in which each participant receives three or more treatments (arms) across successive periods, with random assignment to sequence. Because every participant experiences all arms, the design eliminates between-subject variability from treatment comparisons, dramatically increasing statistical power for a given sample size. It is widely used in clinical pharmacology, psychology, agriculture, and behavioral research.	A crossover randomized controlled trial (crossover RCT) is an experimental design in which each participant receives all study interventions in a randomized sequence, separated by a washout period. Because every participant serves as their own control, within-subject variability is eliminated from the treatment comparison, yielding greater statistical power per participant than a parallel-group RCT of equal size.