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	Thí nghiệm Crossover Full Factorial	Thiết kế Thí nghiệm Thừa số Chéo
Lĩnh vực	Thiết kế thí nghiệm	Thiết kế thí nghiệm
Họ	Process / pipeline	Process / pipeline
Năm ra đời	Mid-to-late 20th century (crossover trials formalised ~1960s–1980s; full factorial DoE from Fisher ~1935)	1920s–1960s (synthesis of factorial and crossover traditions)
Người khởi xướng	Developed within the design-of-experiments tradition (R. A. Fisher and successors); crossover adaptation formalised by B. Jones and M. G. Kenward	R. A. Fisher (factorial principles, 1920s); crossover integration developed in biostatistics through mid-20th century
Loại	Within-subject full factorial experimental design	Experimental design
Công trình gốc	Jones, B., & Kenward, M. G. (2003). Design and Analysis of Cross-Over Trials (2nd ed.). Chapman and Hall/CRC. ISBN: 978-1584883429	Jones, B., & Kenward, M. G. (2014). Design and Analysis of Cross-Over Trials (3rd ed.). Chapman and Hall/CRC. ISBN: 978-1439861424
Tên gọi khác	within-subject full factorial design, repeated-measures full factorial experiment, crossover factorial trial, full factorial crossover design	within-subject factorial design, repeated-measures factorial experiment, factorial crossover trial, crossover factorial trial
Liên quan	6	5
Tóm tắt	A crossover full factorial experiment combines the efficiency of a crossover (within-subject) design with the comprehensiveness of a full factorial design. Every participant receives all combinations of the factor levels across successive treatment periods, separated by washout intervals, allowing complete estimation of all main effects and interactions while using each participant as their own control.	A crossover factorial experiment combines two powerful design principles: factorial structure, which studies multiple factors and their interactions simultaneously, and crossover structure, in which each participant receives more than one treatment combination across sequential periods. By serving as their own control, participants reduce between-subject variability, improving statistical power while also revealing how different factor levels interact within the same individual.