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Đo góc tiếp xúc bằng goniometry×Phân tích Cơ động Lực học×Độ trương nở và phân hủy×
Lĩnh vựcVật liệu sinh họcVật liệu sinh họcVật liệu sinh học
HọProcess / pipelineProcess / pipelineProcess / pipeline
Năm ra đời180519601960
Người khởi xướngThomas YoungFerry and SchwarzlWichterle and Lim
LoạiWettability measurementRheological characterizationKinetic assay
Công trình gốcYoung, T. (1805). An essay on the cohesion of fluids. Philosophical Transactions of the Royal Society, 95, 65-87. link ↗Menard, K. P. (2008). Dynamic mechanical analysis: a practical introduction (2nd ed.). CRC Press. link ↗Wichterle, O., & Lim, D. (1960). Hydrophilic gels for biological use. Nature, 185(4706), 117-118. DOI ↗
Tên gọi khácsessile drop method, contact angle measurement, wettability analysisDMA, rheological analysis, viscoelastic testinghydrogel swelling, polymer degradation, mass loss assay
Liên quan334
Tóm tắtContact angle goniometry is a technique for measuring the wettability of a solid surface by determining the angle at which a liquid droplet meets the surface. Rooted in Thomas Young's thermodynamic analysis from 1805, the method uses optical measurement of droplet profile to quantify surface energy and hydrophilicity. It is indispensable in biomaterials characterization, helping researchers assess whether a scaffold or implant surface will promote or inhibit cell adhesion, protein adsorption, and biointegration.Dynamic mechanical analysis (DMA) measures the viscoelastic properties of materials—their elastic stiffness and viscous damping—by applying a sinusoidal stress or strain and measuring the phase lag and amplitude of the material's response. Developed from rheology principles in the 1960s and formalized by Ferry, Schwarzl, and others, DMA provides quantitative measures of how polymeric biomaterials respond to time-dependent and frequency-dependent mechanical stimuli. Key outputs include the storage modulus (elastic component), loss modulus (viscous component), and loss tangent (tan δ), which together characterize the material's mechanical behavior across temperature and frequency ranges.The swelling and degradation assay measures how biomaterial scaffolds absorb water (swelling) and lose mass over time due to degradation. Developed by Wichterle and Lim in 1960 for hydrogels, the assay is fundamental for characterizing hydrogels, synthetic polymers, and composite scaffolds intended for tissue engineering. The assay provides quantitative data on swelling kinetics (equilibrium water content, swelling ratio), degradation kinetics (mass loss rate, half-life), and mechanisms of degradation (chain scission, enzymatic breakdown).
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ScholarGateSo sánh phương pháp: Contact Angle Goniometry · Dynamic Mechanical Analysis · Swelling and Degradation. Truy cập ngày 2026-06-19 từ https://scholargate.app/vi/compare