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Lý thuyết Coalescent×Quét chọn lọc (Tajima's D)×
Lĩnh vựcDi truyền họcDi truyền học
HọProcess / pipelineProcess / pipeline
Năm ra đời19821989
Người khởi xướngJohn KingmanFumio Tajima
LoạiStochastic process modelNeutrality test
Công trình gốcKingman, J. F. C. (1982). The coalescent. Stochastic Processes and their Applications, 13(3), 235–248. DOI ↗Tajima, F. (1989). Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics, 123(3), 585–595. DOI ↗
Tên gọi khácKingman Coalescent, n-coalescentTajima's D test, Selective sweep analysis, Neutrality test
Liên quan44
Tóm tắtCoalescent theory is a probabilistic framework that traces the genealogical history of DNA sequences backward in time to their most recent common ancestor. Developed by John Kingman in 1982, this method forms the foundation of modern population genetics, enabling researchers to understand demographic events, estimate genetic parameters, and reconstruct evolutionary histories from modern genetic data.Tajima's D is a statistical test designed to detect selective sweeps—recent, rapid fixation of advantageous mutations—from patterns of genetic variation in DNA sequences. Developed by Fumio Tajima in 1989, this test measures deviations from neutrality by comparing different measures of DNA sequence diversity. A significant Tajima's D value indicates departure from neutral evolution, suggesting positive selection, population structure, or demographic events.
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ScholarGateSo sánh phương pháp: Coalescent Theory · Selection Sweep (Tajima's D). Truy cập ngày 2026-06-18 từ https://scholargate.app/vi/compare