So sánh phương pháp

	Thử nghiệm kiểm soát ngẫu nhiên theo cụm	Phép thử kiểm soát ngẫu nhiên theo thừa số
Lĩnh vực	Thiết kế thí nghiệm	Thiết kế thí nghiệm
Họ	Process / pipeline	Process / pipeline
Năm ra đời	1978–1980s	1926 (Fisher factorial foundations); 2000s–2010s (clinical factorial RCT formalization)
Người khởi xướng	Cornfield (1978); systematised by Donner and colleagues (1980s)	R. A. Fisher (factorial design foundations); adapted into clinical trials via MOST framework (Collins et al., 2014)
Loại	Experimental design	Experimental trial design
Công trình gốc	Donner, A., & Klar, N. (2000). Design and Analysis of Cluster Randomization Trials in Health Research. Arnold. ISBN: 978-0340652978	Collins, L. M., Dziak, J. J., Kugler, K. C., & Trail, J. B. (2014). Factorial experiments: Efficient tools for evaluation of intervention components. American Journal of Preventive Medicine, 47(4), 498–504.
Tên gọi khác	cluster RCT, group-randomized trial, community randomized trial, cluster-randomized experiment	Factorial RCT, factorial trial, multi-factor RCT, factorial experiment with randomization
Liên quan	4	6
Tóm tắt	A cluster randomized controlled trial (cluster RCT) is an experimental design in which intact social or organisational groups — such as schools, clinics, villages, or workplaces — are randomly assigned to treatment conditions rather than individual participants. Outcomes are still measured at the individual level, but the unit of randomization is the cluster. This design is essential when an intervention is delivered to whole groups, when there is a risk of contamination between participants in the same setting, or when individual randomization is logistically or ethically impractical.	A factorial randomized controlled trial (factorial RCT) is an experimental design in which participants are randomly assigned to every possible combination of two or more independent factors (treatments or intervention components) simultaneously. This allows researchers to estimate the main effect of each factor and their interactions within a single, efficient trial, rather than running separate experiments for each factor.