So sánh phương pháp

	Thử nghiệm thích ứng ngẫu nhiên theo cụm	Thử nghiệm kiểm soát ngẫu nhiên theo cụm
Lĩnh vực	Thiết kế thí nghiệm	Thiết kế thí nghiệm
Họ	Process / pipeline	Process / pipeline
Năm ra đời	2000s–2010s	1978–1980s
Người khởi xướng	Synthesised from cluster randomization methodology (Donner, 1978; Donner & Klar, 2000) and adaptive design frameworks (Bauer & Kohne, 1994; Pallmann et al., 2018)	Cornfield (1978); systematised by Donner and colleagues (1980s)
Loại	Experimental design	Experimental design
Công trình gốc	Hayes, R. J., & Moulton, L. H. (2017). Cluster Randomised Trials (2nd ed.). CRC Press / Chapman & Hall. ISBN: 978-1498728225	Donner, A., & Klar, N. (2000). Design and Analysis of Cluster Randomization Trials in Health Research. Arnold. ISBN: 978-0340652978
Tên gọi khác	adaptive cluster RCT, adaptive group-randomized trial, cluster adaptive design, adaptive cluster trial	cluster RCT, group-randomized trial, community randomized trial, cluster-randomized experiment
Liên quan	5	4
Tóm tắt	A cluster randomized adaptive experiment combines two methodological principles: (1) intact groups such as schools, clinics, or villages are randomly assigned to treatment conditions rather than individuals, and (2) pre-specified rules allow the design to be modified during the trial based on accumulating cluster-level data. Adaptations may include dropping underperforming arms, reallocating clusters, or adjusting sample size, while maintaining statistical validity and controlling Type I error.	A cluster randomized controlled trial (cluster RCT) is an experimental design in which intact social or organisational groups — such as schools, clinics, villages, or workplaces — are randomly assigned to treatment conditions rather than individual participants. Outcomes are still measured at the individual level, but the unit of randomization is the cluster. This design is essential when an intervention is delivered to whole groups, when there is a risk of contamination between participants in the same setting, or when individual randomization is logistically or ethically impractical.