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| Chuỗi ca bệnh× | Nghiên cứu thuần tập× | |
|---|---|---|
| Lĩnh vực | Dịch tễ học | Dịch tễ học |
| Họ | Process / pipeline | Process / pipeline |
| Năm ra đời≠ | Longstanding; systematized in 20th century clinical research | Mid-20th century (formal epidemiological design codified ~1950s) |
| Người khởi xướng≠ | Historical clinical practice; formalized in modern evidence-based medicine literature | Doll & Hill (British Doctors Study, 1951); Snow (cholera, 1854) |
| Loại≠ | Observational descriptive study | Observational longitudinal study design |
| Công trình gốc≠ | Case series. Wikipedia. link ↗ | Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641 |
| Tên gọi khác | case series report, clinical case series, consecutive case series, patient series | longitudinal study, follow-up study, panel study, incidence study |
| Liên quan≠ | 5 | 6 |
| Tóm tắt≠ | A case series is a descriptive observational study that documents the characteristics, clinical course, and outcomes of a group of patients who share a common condition, exposure, or intervention. Unlike case reports, which focus on a single patient, a case series aggregates data across multiple patients (typically three or more) to identify patterns, generate hypotheses, and characterize rare or novel conditions — without a concurrent control group. | A cohort study assembles a group of individuals who share a common starting point — typically freedom from the outcome of interest — and follows them over time to observe who develops the outcome. By comparing incidence rates between exposed and unexposed subgroups, researchers can estimate relative risk and absolute risk differences. Cohort studies are the gold-standard observational design for measuring disease incidence and establishing temporal relationships between exposure and outcome. |
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