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| Thiết kế thử nghiệm Tiền kiểm-Hậu kiểm Thích ứng× | Nghiên cứu đối chứng ngẫu nhiên (RCT)× | |
|---|---|---|
| Lĩnh vực | Thiết kế thí nghiệm | Thiết kế thí nghiệm |
| Họ≠ | Process / pipeline | Hypothesis test |
| Năm ra đời≠ | 2000s (integration of adaptive principles with classic pre-post structure) | 1948 |
| Người khởi xướng≠ | Synthesizes Campbell & Stanley (1963) pretest-posttest framework with adaptive design methodology formalized by Chow & Chang (2000s) | James Lind (early precursor, 1747); modern formulation: Austin Bradford Hill & Medical Research Council (1948) |
| Loại≠ | Experimental design | Interventional comparative study |
| Công trình gốc≠ | Campbell, D. T., & Stanley, J. C. (1963). Experimental and Quasi-Experimental Designs for Research. Rand McNally. link ↗ | Schulz, K.F., Altman, D.G., Moher, D., for the CONSORT Group (2010). CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials. BMJ, 340, c332. DOI ↗ |
| Tên gọi khác | adaptive pre-post design, adaptive pretest-posttest trial, adaptive two-period design, pre-post adaptive experiment | RCT, randomised controlled trial, clinical trial, Randomize Kontrollü Çalışma (RCT) Tasarımı |
| Liên quan≠ | 6 | 7 |
| Tóm tắt≠ | An adaptive pretest-posttest experimental design measures all participants before and after an intervention while allowing pre-specified modifications to the trial — such as sample size re-estimation, treatment arm dropping, or randomization ratio adjustment — based on accumulated interim data. It combines the interpretive power of change-score analysis with the efficiency gains and ethical safeguards of adaptive methodology, making it particularly valuable in clinical, educational, and behavioral research where early data can inform better resource allocation. | A randomized controlled trial (RCT) is the gold standard experimental design in clinical and health research, in which participants are randomly allocated to a treatment group or a control group so that the effect of an intervention can be measured with the highest possible degree of internal validity. The modern parallel-group RCT was formalized by Austin Bradford Hill and the Medical Research Council in their landmark streptomycin trial of 1948, and its reporting is governed today by the CONSORT 2010 guidelines (Schulz et al., 2010). |
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