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Thiết kế Thử nghiệm Đa Cánh Thích ứng×Thí nghiệm đa nhánh×
Lĩnh vựcThiết kế thí nghiệmThiết kế thí nghiệm
HọProcess / pipelineProcess / pipeline
Năm ra đời2000s–2010s (MAMS framework formalized c. 2003–2011)1990s–2000s (clinical formalization); multi-arm concept implicit in ANOVA-era factorial designs
Người khởi xướngPatrick Royston, Mahesh Parmar, and colleagues (multi-arm multi-stage framework); further developed by James Wason, Thomas Jaki and othersDeveloped within clinical trials methodology; formalized by Parmar, Royston and colleagues (UK MRC CTU, early 2000s)
LoạiExperimental designExperimental design
Công trình gốcRoyston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256. DOI ↗Royston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256. DOI ↗
Tên gọi khácMAMS design, multi-arm adaptive trial, adaptive platform trial, response-adaptive multi-arm experimentmulti-arm trial, multiple-arm experiment, multi-group experiment, many-arm design
Liên quan35
Tóm tắtAn adaptive multi-arm experiment simultaneously evaluates several treatment conditions against a common control and modifies the trial in real time based on accumulating data — dropping ineffective arms early, reallocating participants toward promising ones, or adjusting sample sizes — all while controlling error rates. The approach maximizes information gained per participant and reduces the time and cost required to identify effective treatments relative to running sequential separate trials.A multi-arm experiment simultaneously compares three or more treatment or intervention conditions — each called an arm — against a shared control or against one another. By testing multiple alternatives in a single study, it yields more information per participant than running separate two-group experiments sequentially, while controlling the overall Type I error rate through pre-specified comparison strategies.
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ScholarGateSo sánh phương pháp: Adaptive Multi-Arm Experiment · Multi-arm experiment. Truy cập ngày 2026-06-17 từ https://scholargate.app/vi/compare