Порівняння методів
Переглядайте обрані методи поруч; рядки з відмінностями підсвічено.
| SERS× | Поверхневий плазмонний резонанс× | |
|---|---|---|
| Галузь | Спектроскопія | Спектроскопія |
| Родина | Process / pipeline | Process / pipeline |
| Рік появи≠ | 1974 | 1971 |
| Автор методу≠ | Martin Fleischmann | Erich Kretschmann |
| Тип≠ | Vibrational spectroscopy technique | Optical technique |
| Основоположне джерело≠ | Fleischmann, M., Hendra, P. J., & McQuillan, A. J. (1974). Raman spectra of pyridine adsorbed at a silver electrode. Chemical Physics Letters, 26(2), 163-166. DOI ↗ | Kretschmann, E. (1971). Determination of optical constants of metals by excitation of surface plasmons. Zeitschrift für Physik, 241(4), 313-324. link ↗ |
| Інші назви≠ | Surface-enhanced Raman scattering, SERS spectroscopy | SPR, surface plasmon, SPR biosensing |
| Пов'язані | 3 | 3 |
| Підсумок≠ | Surface-Enhanced Raman Spectroscopy (SERS) amplifies weak Raman signals by many orders of magnitude when analyte molecules are adsorbed on specially prepared metal (typically silver or gold) nanostructured surfaces. Discovered by Fleischmann, Hendra, and McQuillan in 1974, SERS enables detection of vibrational signatures of single molecules and ultra-trace contaminants, revolutionizing analytical chemistry and forensics. | Surface Plasmon Resonance (SPR) is a real-time, label-free technique for detecting and monitoring biomolecular interactions at a sensor surface by measuring changes in the refractive index caused by ligand binding. Developed by Kretschmann in 1971 and applied to biosensing by Liedberg, Nylander, and Lundström in 1983, SPR is now a gold standard for measuring binding kinetics (association and dissociation rates) and equilibrium binding constants in protein interactions, antibody-antigen recognition, and drug discovery. |
| ScholarGateНабір даних ↗ |
|
|