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Прагматичне екологічне дослідження×Прагматичне рандомізоване контрольоване дослідження×
ГалузьЕпідеміологіяЕпідеміологія
РодинаProcess / pipelineProcess / pipeline
Рік появи1967–1982 (pragmatic concept 1967; ecological study formalized ~1982)1967
Автор методуMorgenstern (ecological study framework); Schwartz & Lellouch (pragmatic design concept)Daniel Schwartz & Joseph Lellouch
ТипObservational ecological study with pragmatic framingInterventional study design
Основоположне джерелоMorgenstern, H. (1982). Uses of ecologic analysis in epidemiologic research. American Journal of Public Health, 72(12), 1336–1344. DOI ↗Schwartz, D., & Lellouch, J. (1967). Explanatory and pragmatic attitudes in therapeutical trials. Journal of Chronic Diseases, 20(8), 637–648. DOI ↗
Інші назвиreal-world ecological study, effectiveness ecological study, population-level pragmatic study, pragmatic ecologic designpragmatic RCT, effectiveness trial, real-world RCT, practical clinical trial
Пов'язані56
ПідсумокA pragmatic ecological study is an observational epidemiological design that examines associations between exposures and outcomes at the population or group level — using routinely collected, real-world data — with the explicit goal of informing practical public health decisions under everyday conditions. Rather than controlling every variable in a laboratory-like manner, it embraces the complexity and heterogeneity of natural settings to answer effectiveness questions relevant to policy.A pragmatic randomized clinical trial (pragmatic RCT) is an interventional study that tests whether a treatment works under routine clinical conditions, as opposed to the tightly controlled setting of an explanatory trial. It prioritizes broad eligibility, flexible delivery, and patient-relevant outcomes to answer the question 'Does this treatment work in everyday practice?' rather than 'Can this treatment work under ideal circumstances?' The distinction between pragmatic and explanatory trials was formally articulated by Schwartz and Lellouch in 1967 and operationalized by the PRECIS tool in 2009.
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ScholarGateПорівняння методів: Pragmatic ecological study · Pragmatic randomized clinical trial. Отримано 2026-06-19 з https://scholargate.app/uk/compare