Порівняння методів
Переглядайте обрані методи поруч; рядки з відмінностями підсвічено.
| КОСІ× | ЯМР спін-ехо× | |
|---|---|---|
| Галузь | Спектроскопія | Спектроскопія |
| Родина | Process / pipeline | Process / pipeline |
| Рік появи≠ | 1976 | 1950 |
| Автор методу≠ | Wüthrich Kurt | Erwin Hahn |
| Тип≠ | Two-dimensional pulse sequence | Spectroscopic pulse sequence |
| Основоположне джерело≠ | Aue, W. P., Bartholdi, E., & Ernst, R. R. (1976). Two-dimensional spectroscopy. Application to nuclear magnetic resonance. The Journal of Chemical Physics, 64(5), 2229-2246. DOI ↗ | Hahn, E. L. (1950). Spin echoes. Physical Review, 80(4), 580-594. DOI ↗ |
| Інші назви≠ | COSY NMR, 2D COSY, 1H-1H COSY | CPMG pulse sequence, spin-echo NMR |
| Пов'язані | 4 | 4 |
| Підсумок≠ | Correlation Spectroscopy (COSY) is a two-dimensional NMR technique that correlates proton chemical shifts through scalar coupling (J-coupling), revealing which protons are magnetically coupled and hence bonded through multiple bonds. Developed by Aue, Bartholdi, and Ernst in 1976, COSY became one of the most important tools in structural elucidation, enabling chemists to map out proton connectivity patterns and deduce molecular topology without isotopic labeling. | The spin-echo is a fundamental nuclear magnetic resonance (NMR) pulse sequence technique introduced by Erwin Hahn in 1950. It uses a 90-degree radiofrequency pulse followed by a 180-degree refocusing pulse to create an echo, effectively reversing the effects of magnetic field inhomogeneities and allowing accurate measurement of spin relaxation properties. This technique is essential in modern NMR spectroscopy for both one-dimensional and multidimensional experiments. |
| ScholarGateНабір даних ↗ |
|
|