MICE — Multivariate Imputation by Chained Equations

Multivariate Imputation by Chained Equations (MICE) is an iterative procedure for handling missing data in multivariate datasets. Introduced by Stef van Buuren and Karin Groothuis-Oudshoorn through the R package mice (2011), the algorithm fills each missing variable using a separate regression model conditioned on all other variables, cycling through variables repeatedly until the imputed values converge. The result is m completed datasets that are analysed separately and combined using Rubin's rules.