Matched Case-Crossover Design
The matched case-crossover design is a self-controlled observational study in which each case serves as its own control. A short hazard window immediately before the acute event is compared with one or more matched control windows — selected to have the same day of week, season, or other time-varying covariate — making the design robust to stable individual confounders and calendar-time trends simultaneously.
Rekodi ya chanzo
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- Maclure, M. (1991). The case-crossover design: a method for studying transient effects on the risk of acute events. American Journal of Epidemiology, 133(2), 144–153. · DOI 10.1093/oxfordjournals.aje.a115853
- Lumley, T., & Levy, D. (2000). Bias in the case-crossover design: implications for studies of air pollution. Environmetrics, 11(6), 689–704. · DOI 10.1002/1099-095x(200011/12)11:6<689::aid-env439>3.0.co;2-n
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