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	Sequential Organ Failure Assessment Score	APACHE II-skår	Modified Early Warning Score
Ämnesområde	Klinisk bedömning	Klinisk bedömning	Klinisk bedömning
Familj	Process / pipeline	Process / pipeline	Process / pipeline
Ursprungsår	1996	1985	2001
Upphovsperson	Jean-Louis Vincent and Rui Moreno	William A. Knaus, et al.	Christian P. Subbe, et al.
Typ	Organ dysfunction and sepsis assessment	ICU severity and mortality prediction	Hospital ward deterioration warning system
Ursprungskälla	Vincent, J. L., Moreno, R., Takala, J., et al. (1996). The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfuncti on/failure. Intensive Care Medicine, 22(7), 707-710.	Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1985). APACHE II: a severity of disease classification system. Critical Care Medicine, 13(10), 818-829.	Subbe, C. P., Kruger, M., Rutherford, P., & Gemmel, L. (2001). Validation of a modified Early Warning Score in medical admissions. QJM: An International Journal of Medicine, 94(10), 521-526.
Alias	SOFA, Sepsis-related Organ Failure Assessment	APACHE-II, APACHE2	MEWS, Early warning score
Närliggande	3	3	3
Sammanfattning	The Sequential Organ Failure Assessment (SOFA) score, introduced by Vincent and Moreno in 1996, is a 24-point daily assessment tool that quantifies organ dysfunction across six physiological systems in critically ill patients. It was adopted into the 2016 Sepsis-3 definitions and is now the international standard for identifying and grading sepsis-related organ failure.	The Acute Physiology and Chronic Health Evaluation (APACHE) II score, introduced by Knaus et al. in 1985, is a 71-point severity of illness classification system for critically ill patients. It combines acute physiological parameters, age, and chronic health status to predict intensive care unit (ICU) mortality, facilitating patient risk stratification and research standardization.	The Modified Early Warning Score (MEWS), introduced by Subbe et al. in 2001, is a 14-point alert system designed for rapid detection of clinical deterioration in hospitalized patients. It combines six vital sign and laboratory parameters to identify patients at high risk of rapid decline, enabling early intervention before critical events occur.