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	DTI Tractography	Magnetresonanselastografi
Ämnesområde	Medicinsk avbildning	Medicinsk avbildning
Familj	Process / pipeline	Process / pipeline
Ursprungsår	1999	1995
Upphovsperson	Peter Basser	Richard Muthupillai
Typ	Fiber tracking from diffusion MRI	MRI-based measurement of tissue stiffness
Ursprungskälla	Basser, P. J., Mattiello, J., LeBihan, D. (1994). Estimation of the effective self-diffusion tensor from the NMR spin echo. Journal of Magnetic Resonance, Series B, 103(3), 247-254.	Muthupillai, R., Lomas, D. J., Rossman, P. J., et al. (1995). Magnetic resonance elastography by direct visualization of propagating acoustic strain waves. Science, 269(5232), 1854-1857.
Alias	Diffusion tensor tractography, White matter tractography, Fiber tracking	MRE, elastography, tissue stiffness mapping
Närliggande	5	5
Sammanfattning	Diffusion Tensor Imaging Tractography (DTI tractography) is a non-invasive neuroimaging technique that maps white matter fiber bundles in the brain by tracking the three-dimensional diffusion of water molecules along axons. Pioneered by Basser, Mori, and Conturo in the 1990s, DTI tractography reveals the structural connectivity of the brain, enabling visualization of major pathways (corpus callosum, arcuate fasciculus, corticospinal tract) and assessment of fiber integrity. It is widely used in neurosurgical planning, neurological disease assessment, and brain connectivity research.	Magnetic Resonance Elastography (MRE) is a non-invasive imaging technique that measures tissue stiffness by encoding the motion of acoustic shear waves into MRI signal and calculating the elastic modulus from wave propagation patterns. Developed by Muthupillai and colleagues in 1995, MRE enables quantitative assessment of tissue mechanics, particularly useful for diagnosing liver fibrosis, cardiac dysfunction, and neurological diseases. It has emerged as a non-invasive alternative to biopsy for staging hepatic fibrosis and is expanding into other organ systems.