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	Alzheimer's Disease Assessment Scale-Cognitive	Mattis Demensskala
Ämnesområde	Neuropsykologi	Neuropsykologi
Familj	Process / pipeline	Process / pipeline
Ursprungsår	1984	1988
Upphovsperson	William Rosen	Sandra Mattis
Typ	Clinician-administered cognitive scale for Alzheimer's disease	Clinician-administered comprehensive neuropsychological scale
Ursprungskälla	Rosen, W. G., Mohs, R. C., & Davis, K. L. (1984). A new rating scale for Alzheimer's disease. American Journal of Psychiatry, 141(11), 1356-1364.	Mattis, S. (1988). Dementia Rating Scale (DRS). Odessa, FL: Psychological Assessment Resources.
Alias	ADAS-Cog, ADAS-Cog14, ADAS-Cog13	DRS, Mattis DRS, Dementia Rating Scale
Närliggande	5	5
Sammanfattning	The Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) is a clinician-administered cognitive assessment instrument designed specifically to measure cognitive decline in Alzheimer's disease. Developed by Rosen, Mohs, and Davis in 1984 and published in the American Journal of Psychiatry, the ADAS-Cog has become the gold standard outcome measure in pharmaceutical trials of antidementia drugs. It is sensitive to disease progression and capable of detecting cognitive change over periods as brief as 6–12 months.	The Mattis Dementia Rating Scale (DRS) is a comprehensive 36-item clinician-administered neuropsychological battery designed to assess and quantify cognitive decline in dementia. Developed by Sandra Mattis in 1988, the DRS measures five major cognitive domains—attention, initiation/perseveration, construction, conceptualization, and memory—and provides both a total score and subscale scores. The DRS is particularly valued in neurodegenerative disease research and clinical settings for its sensitivity to cognitive change over time and its utility in detecting cognitive impairment across the dementia spectrum.