Сравнение методов
Просматривайте выбранные методы рядом; строки с различиями подсвечены.
| Поверхностный плазмонный резонанс× | SERS× | |
|---|---|---|
| Область | Спектроскопия | Спектроскопия |
| Семейство | Process / pipeline | Process / pipeline |
| Год появления≠ | 1971 | 1974 |
| Автор метода≠ | Erich Kretschmann | Martin Fleischmann |
| Тип≠ | Optical technique | Vibrational spectroscopy technique |
| Основополагающий источник≠ | Kretschmann, E. (1971). Determination of optical constants of metals by excitation of surface plasmons. Zeitschrift für Physik, 241(4), 313-324. link ↗ | Fleischmann, M., Hendra, P. J., & McQuillan, A. J. (1974). Raman spectra of pyridine adsorbed at a silver electrode. Chemical Physics Letters, 26(2), 163-166. DOI ↗ |
| Другие названия≠ | SPR, surface plasmon, SPR biosensing | Surface-enhanced Raman scattering, SERS spectroscopy |
| Связанные | 3 | 3 |
| Сводка≠ | Surface Plasmon Resonance (SPR) is a real-time, label-free technique for detecting and monitoring biomolecular interactions at a sensor surface by measuring changes in the refractive index caused by ligand binding. Developed by Kretschmann in 1971 and applied to biosensing by Liedberg, Nylander, and Lundström in 1983, SPR is now a gold standard for measuring binding kinetics (association and dissociation rates) and equilibrium binding constants in protein interactions, antibody-antigen recognition, and drug discovery. | Surface-Enhanced Raman Spectroscopy (SERS) amplifies weak Raman signals by many orders of magnitude when analyte molecules are adsorbed on specially prepared metal (typically silver or gold) nanostructured surfaces. Discovered by Fleischmann, Hendra, and McQuillan in 1974, SERS enables detection of vibrational signatures of single molecules and ultra-trace contaminants, revolutionizing analytical chemistry and forensics. |
| ScholarGateНабор данных ↗ |
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