Сравнение методов
Просматривайте выбранные методы рядом; строки с различиями подсвечены.
| Прагматичный полный факторный эксперимент× | Прагматичное рандомизированное контролируемое исследование× | |
|---|---|---|
| Область | Планирование эксперимента | Планирование эксперимента |
| Семейство | Process / pipeline | Process / pipeline |
| Год появления≠ | 1920s (factorial); 1967/2009 (pragmatic framework) | 1967 |
| Автор метода≠ | Full factorial: R.A. Fisher (1920s); Pragmatic framing: Schwartz & Lellouch (1967), formalized by Thorpe et al. (2009) | Daniel Schwartz and Joseph Lellouch |
| Тип≠ | Experimental design | Experimental design — pragmatic trial |
| Основополагающий источник≠ | Thorpe, K. E., Zwarenstein, M., Oxman, A. D., Treweek, S., Furberg, C. D., Altman, D. G., ... & Chalmers, I. (2009). A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers. Journal of Clinical Epidemiology, 62(5), 464-475. DOI ↗ | Schwartz, D., & Lellouch, J. (1967). Explanatory and pragmatic attitudes in therapeutical trials. Journal of Chronic Diseases, 20(8), 637–648. DOI ↗ |
| Другие названия | pragmatic factorial trial, real-world full factorial design, effectiveness full factorial experiment, pragmatic 2^k experiment | pRCT, pragmatic trial, practical clinical trial, real-world RCT |
| Связанные≠ | 6 | 4 |
| Сводка≠ | A pragmatic full factorial experiment combines the complete crossing of all factor levels (the full factorial structure) with the broad eligibility criteria, flexible delivery, and real-world conditions of a pragmatic trial. Every possible combination of factors is tested simultaneously, yielding both main effects and all interaction effects, while deliberately relaxing strict laboratory controls to reflect how interventions actually operate in practice. | A pragmatic randomized controlled trial (pRCT) tests whether an intervention works under ordinary, real-world conditions — broad eligibility, flexible delivery, and routine care settings. Participants are still randomly assigned to treatment or control, preserving causal inference, but the study is designed to reflect the diversity and variability of actual practice rather than the ideal conditions of an explanatory trial. The defining framework is the PRECIS-2 tool, which maps any RCT along nine pragmatic-to-explanatory dimensions. |
| ScholarGateНабор данных ↗ |
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