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Спин-эхо ЯМР×КОСИ×
ОбластьСпектроскопияСпектроскопия
СемействоProcess / pipelineProcess / pipeline
Год появления19501976
Автор методаErwin HahnWüthrich Kurt
ТипSpectroscopic pulse sequenceTwo-dimensional pulse sequence
Основополагающий источникHahn, E. L. (1950). Spin echoes. Physical Review, 80(4), 580-594. DOI ↗Aue, W. P., Bartholdi, E., & Ernst, R. R. (1976). Two-dimensional spectroscopy. Application to nuclear magnetic resonance. The Journal of Chemical Physics, 64(5), 2229-2246. DOI ↗
Другие названияCPMG pulse sequence, spin-echo NMRCOSY NMR, 2D COSY, 1H-1H COSY
Связанные44
СводкаThe spin-echo is a fundamental nuclear magnetic resonance (NMR) pulse sequence technique introduced by Erwin Hahn in 1950. It uses a 90-degree radiofrequency pulse followed by a 180-degree refocusing pulse to create an echo, effectively reversing the effects of magnetic field inhomogeneities and allowing accurate measurement of spin relaxation properties. This technique is essential in modern NMR spectroscopy for both one-dimensional and multidimensional experiments.Correlation Spectroscopy (COSY) is a two-dimensional NMR technique that correlates proton chemical shifts through scalar coupling (J-coupling), revealing which protons are magnetically coupled and hence bonded through multiple bonds. Developed by Aue, Bartholdi, and Ernst in 1976, COSY became one of the most important tools in structural elucidation, enabling chemists to map out proton connectivity patterns and deduce molecular topology without isotopic labeling.
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ScholarGateСравнение методов: NMR Spin-Echo · COSY. Получено 2026-06-18 из https://scholargate.app/ru/compare