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Вложенное случай-контроль исследование (nested case-control study)×Исследование «случай-контроль»×
ОбластьЭпидемиологияЭпидемиология
СемействоProcess / pipelineProcess / pipeline
Год появления1973–19771950s (formal methodology); precursors in the 1920s
Автор методаNathan Mantel (1973); D. C. Thomas (1977 formalization)Janet Lane-Claypon (early precursors, 1926); formalized by Brian MacMahon and Jerome Cornfield in the 1950s–1960s
ТипHybrid observational study designObservational analytic study design
Основополагающий источникThomas, D. C. (1977). Addendum to: Methods of cohort analysis: Appraisal by application to asbestos mining. Journal of the Royal Statistical Society, Series A, 140(4), 469–491. link ↗Schlesselman, J.J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195027860
Другие названияNCC study, nested CC design, case-control within cohort, density sampling case-controlcase-referent study, case-control design, retrospective case-control, case-control analysis
Связанные66
СводкаA nested case-control study is an efficient observational design embedded within a defined cohort. For each participant who develops the outcome of interest (a case), a small number of matched controls are sampled from those still at risk at the same point in time. This density-sampling strategy yields odds ratios that approximate incidence-rate ratios from the full cohort at a fraction of the data-collection cost — making it the preferred alternative when measuring exposures for all cohort members would be prohibitively expensive or technically demanding.A case-control study is a retrospective observational design in which individuals who have developed a disease or outcome of interest (cases) are compared with individuals who have not (controls) to determine whether prior exposure to a putative risk factor differs between the two groups. The primary measure of association is the odds ratio, which approximates the relative risk when the outcome is rare. Case-control studies are especially efficient for investigating rare diseases and generating etiological hypotheses.
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ScholarGateСравнение методов: Nested case-control · Case-control study. Получено 2026-06-15 из https://scholargate.app/ru/compare