Optimization-assisted central composite design
Optimization-assisted central composite design (CCD) combines the rotatable, second-order experimental layout of central composite design with mathematical optimization algorithms — typically desirability functions, response surface optimization, or metaheuristics — to find the factor settings that simultaneously maximize, minimize, or hit target values for one or more response variables. It is the most widely applied response-surface optimization workflow in chemical, pharmaceutical, food science, and manufacturing engineering.
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- Myers, R. H., Montgomery, D. C., & Anderson-Cook, C. M. (2009). Response Surface Methodology: Process and Product Optimization Using Designed Experiments (3rd ed.). Wiley. · ISBN 978-0470174463
- Derringer, G., & Suich, R. (1980). Simultaneous optimization of several response variables. Journal of Quality Technology, 12(4), 214–219. · DOI 10.1080/00224065.1980.11980968
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