Bayesian Case-Crossover Design
The Bayesian case-crossover design is a self-matched epidemiological method that estimates the transient effect of a time-varying exposure on the risk of an acute event. Each case serves as their own control, eliminating confounding by time-stable individual characteristics. Bayesian inference replaces or supplements the classical conditional logistic regression, enabling the incorporation of prior knowledge, more stable estimation in sparse data, and full uncertainty quantification via posterior distributions.
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- Maclure, M. (1991). The case-crossover design: a method for studying transient effects on the risk of acute events. American Journal of Epidemiology, 133(2), 144–153. · DOI 10.1093/oxfordjournals.aje.a115853
- Janes, H., Sheppard, L., & Lumley, T. (2005). Case-crossover analyses of air pollution exposure data: referent selection strategies and their implications for bias. Epidemiology, 16(6), 717–726. · DOI 10.1097/01.ede.0000181315.18836.9d
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