Methoden vergelijken

	Gevoeligheidsanalyse met Centraal Composiet Ontwerp	Response Surface Methodology (RSM)
Vakgebied	Experimenteel ontwerp	Experimenteel ontwerp
Familie	Process / pipeline	Hypothesis test
Jaar van ontstaan	1951 (CCD); SA integration throughout 1970s–2000s	1951
Grondlegger	G. E. P. Box and K. B. Wilson (CCD); sensitivity analysis formalised within RSM by Montgomery and subsequent practitioners	George E. P. Box & K. B. Wilson
Type	Quantitative experimental design with post-hoc sensitivity assessment	Second-order polynomial response surface model
Oorspronkelijke bron	Box, G. E. P., & Wilson, K. B. (1951). On the Experimental Attainment of Optimum Conditions. Journal of the Royal Statistical Society: Series B, 13(1), 1–45.	Box, G. E. P. & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society, Series B, 13(1), 1–45.
Aliassen	SA-CCD, CCD sensitivity analysis, RSM sensitivity analysis, response surface sensitivity study	RSM, Central Composite Design, Box-Behnken Design, CCD
Verwant	4	7
Samenvatting	Sensitivity analysis with Central Composite Design (CCD) combines a structured, space-filling experimental layout with a systematic examination of how much each input factor drives changes in the response. CCD supports estimation of a full quadratic response surface model; sensitivity analysis then interrogates that model to rank factors by influence, identify interactions, and map the performance landscape — guiding engineers and researchers toward robust operating conditions and efficient optimisation.	Response Surface Methodology is a collection of statistical and mathematical techniques for building an empirical second-order polynomial model that relates a continuous response variable to two or more controllable input factors, and then locating the factor settings that optimize that response. The approach was introduced by George E. P. Box and K. B. Wilson in their landmark 1951 paper and has since become a cornerstone of process optimization across engineering, chemistry, food science, and pharmaceutics.