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Analyse van Speekselbiomarkers×Index voor Dentale Erosie×
VakgebiedTandheelkundeTandheelkunde
FamilieProcess / pipelineProcess / pipeline
Jaar van ontstaan2000s+ (clinical application)1990s+ (systematic indices)
GrondleggerMultiple innovators (Giannobile, Malamud, et al.)Multiple indices (Lussi index, BEWE, etc.)
TypeLaboratory and point-of-care diagnosticsClinical assessment index
Oorspronkelijke bronGiannobile, W. V., McDevitt, J. T., Niedbala, R. S., Malamud, D., & Prozorovsky, T. (2009). Translating molecular diagnostics into clinical practice: Designing the next generation of oral health technologies. Advances in Dental Research, 23(1), 80-89. link ↗Lussi, A., Jaeggi, T., & Zero, D. (2004). The role of diet in the aetiology of dental erosion. Caries Research, 38(1), 34-44. DOI ↗
Aliassensaliva testing, salivary diagnostics, oral biomarker assessmenttooth wear index, erosion severity index, TSL index
Verwant33
SamenvattingSalivary biomarker analysis detects protein, molecular, or microbial markers in saliva that indicate oral and systemic disease. Salivary diagnostics assess risk and activity of dental caries, periodontal disease, oral cancer, and other conditions. Biomarkers include antimicrobial proteins (lysozyme, lactoferrin), inflammatory mediators (interleukins, TNF-alpha), cariogenic bacteria (Streptococcus mutans), and virulence factors. Point-of-care saliva testing offers rapid, non-invasive alternatives to conventional laboratory methods, enabling chairside diagnosis and personalized risk assessment.The Dental Erosion Index is a systematic clinical assessment tool that quantifies the severity of tooth surface loss caused by non-carious erosive agents (acidic substances, mechanical abrasion, or biological factors). Multiple index systems exist (e.g., Lussi Index, Basic Erosive Wear Examination or BEWE), each scoring erosion based on the extent and depth of surface loss on coronal and cervical tooth surfaces. Erosion assessment is critical for identifying patients at risk for advanced tooth loss, determining preventive interventions, and guiding restorative management.
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ScholarGateMethoden vergelijken: Salivary Biomarker Analysis · Dental Erosion Index. Geraadpleegd op 2026-06-20 via https://scholargate.app/nl/compare