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Risico-gecorrigeerde patiënt-controle studie×Logistische Regressie×
VakgebiedEpidemiologieOnderzoeksstatistiek
FamilieProcess / pipelineProcess / pipeline
Jaar van ontstaan1950s–1980s (case-control design from 1950; risk-adjustment conventions established by 1980s)1958
GrondleggerDoll & Hill (foundational case-control); risk adjustment via multivariate logistic regression systematised by Schlesselman (1982) and Breslow & Day (1980)David Roxbee Cox
TypeObservational analytic study designMethod
Oorspronkelijke bronSchlesselman, J. J. (1982). Case-Control Studies: Design, Conduct, Analysis. Oxford University Press. ISBN: 978-0195029697Cox, D. R. (1958). The regression analysis of binary sequences. Journal of the Royal Statistical Society, Series B, 20(2), 215–242. DOI ↗
Aliassenadjusted case-control study, covariate-adjusted case-control, risk-stratified case-control study, matched and adjusted case-control studylogit model, binomial logistic regression, LR
Verwant53
SamenvattingA risk-adjusted case-control study is an observational design that identifies individuals with a disease outcome (cases) and comparable individuals without it (controls), then uses statistical adjustment — most commonly multivariable logistic regression — to estimate the association between an exposure and the outcome while controlling for confounding risk factors. The adjustment step is what distinguishes this variant from a simple case-control study, producing odds ratios that better reflect the independent contribution of the exposure of interest.Logistic regression is a statistical method for modeling the probability of a binary outcome (disease present/absent, success/failure) as a function of continuous and categorical predictors. Developed by David Roxbee Cox (1958), it solves the problem of predicting categorical outcomes by applying a logistic transformation to constrain predictions to the [0,1] probability interval, enabling accurate risk stratification, diagnostic prediction, and causal inference in epidemiology, medicine, and social science.
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ScholarGateMethoden vergelijken: Risk-adjusted case-control study · Logistic Regression. Geraadpleegd op 2026-06-17 via https://scholargate.app/nl/compare