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Pragmatische Casusreeks×Prospectieve Casusreeks×
VakgebiedEpidemiologieEpidemiologie
FamilieProcess / pipelineProcess / pipeline
Jaar van ontstaanPragmatic framing formalized 1967; case series practice predates 20th centuryLate 19th century onward; formalized in modern clinical epidemiology by the 1970s–1980s
GrondleggerPragmatic framework: Schwartz & Lellouch (1967); case series design: longstanding clinical traditionEvolved from clinical case reporting traditions in 19th–20th century medicine
TypeObservational descriptive studyObservational study design
Oorspronkelijke bronSchwartz, D., & Lellouch, J. (1967). Explanatory and pragmatic attitudes in therapeutical trials. Journal of Chronic Diseases, 20(8), 637–648. DOI ↗Meinert, C. L. (1996). Clinical Trials: Design, Conduct, and Analysis. Oxford University Press. ISBN: 978-0195035681
Aliassenreal-world case series, pragmatic observational case series, practice-based case seriesprospective case series study, forward-looking case series, prospective uncontrolled study, prospective observational case series
Verwant55
SamenvattingA pragmatic case series is an observational study that documents consecutive or purposively selected patients receiving a clinical intervention or presenting with a condition under routine, real-world practice conditions — without randomization, a control group, or the highly controlled eligibility criteria characteristic of explanatory trials. It is used to describe treatment patterns, outcomes, and adverse events as they occur in everyday clinical settings.A prospective case series is an observational study design in which a group of patients with a particular condition, exposure, or intervention is identified in advance and followed forward in time according to a pre-specified protocol. Data on outcomes, adverse events, and clinical course are collected as they occur, yielding higher data quality and temporal clarity than retrospective designs. No control group is included, so causal inference is limited, but the design is valuable for characterizing natural disease history, early safety signals, and feasibility of new interventions.
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ScholarGateMethoden vergelijken: Pragmatic case series · Prospective Case Series. Geraadpleegd op 2026-06-19 via https://scholargate.app/nl/compare