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Matched Case Report×Gepaarde case-controlstudie×
VakgebiedEpidemiologieEpidemiologie
FamilieProcess / pipelineProcess / pipeline
Jaar van ontstaanLate 20th century (widely used from 1990s onward in pharmacovigilance and rare-disease literature)1950s–1970s
GrondleggerEvolved from standard clinical case reporting practice; no single originatorBrian MacMahon and others; systematised by Schlesselman (1982)
TypeObservational descriptive design with comparatorObservational analytic design
Oorspronkelijke bronGagnier, J. J., Kienle, G., Altman, D. G., Moher, D., Sox, H., & Riley, D. (2013). The CARE guidelines: consensus-based clinical case reporting guideline development. Journal of Medical Case Reports, 7, 223. DOI ↗Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755474
Aliassenmatched case write-up, case report with matched comparator, matched single-case report, comparator-matched case reportmatched case-referent study, individually matched case-control, pair-matched case-control, matched case-control design
Verwant55
SamenvattingA matched case report is a structured clinical case write-up in which the index patient is compared against one or more systematically selected matched comparators — typically patients with similar demographics, comorbidities, or clinical settings who did not experience the same unusual outcome. The matched comparator contextualises the index case, strengthening causal inference beyond what a conventional single case report can support, and is used particularly in pharmacovigilance, rare-disease documentation, and novel-intervention reporting.A matched case-control study is an observational epidemiological design in which each case (a person with the disease or outcome of interest) is paired with one or more controls (persons without the outcome) who share one or more characteristics — such as age, sex, or clinical setting — to control confounding. Exposure history is then compared between cases and their matched controls to estimate the odds ratio of the exposure-disease association.
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ScholarGateMethoden vergelijken: Matched case report · Matched case-control study. Geraadpleegd op 2026-06-15 via https://scholargate.app/nl/compare