Methoden vergelijken

	Machine Learning-Augmented Instrumental Variables (ML-IV)	Instrumentele Variabelen (IV) Methode voor Causale Inferentie
Vakgebied	Causale inferentie	Gezondheidseconomie
Familie	Regression model	Process / pipeline
Jaar van ontstaan	2012-2018	1990s (modern applications)
Grondlegger	Belloni, Chernozhukov & Hansen; Chernozhukov et al.	Angrist & Pischke (applied econometrics); rooted in econometric theory
Type	Causal inference / semi-parametric estimation	Method
Oorspronkelijke bron	Chernozhukov, V., Chetverikov, D., Demirer, M., Duflo, E., Hansen, C., Newey, W., & Robins, J. (2018). Double/debiased machine learning for treatment and structural parameters. The Econometrics Journal, 21(1), C1-C68.	Angrist, J. D., & Pischke, J. S. (2009). Mostly Harmless Econometrics: An Empiricist's Companion. Princeton: Princeton University Press.
Aliassen	ML-IV, MLIV, Double/Debiased ML with IV, DML-IV	IV, two-stage least squares, TSLS, causal estimation
Verwant	4	3
Samenvatting	Machine learning-augmented instrumental variables combines the causal identification power of classical IV with modern high-dimensional machine learning — using methods such as LASSO, random forests, or neural networks to select valid instruments and model nuisance functions, thereby improving first-stage fit and enabling valid inference even when the number of potential instruments or controls is large relative to the sample size.	Instrumental variables (IV) is an econometric method to estimate causal effects when treatment or exposure is not randomly assigned and confounding is severe or unmeasured. IV relies on a third variable (instrument) that influences treatment but does not directly affect the outcome, allowing researchers to isolate the causal effect from the noise of confounding. Developed extensively in econometrics (Angrist & Pischke, 1990s–2000s), IV methods are increasingly used in health economics and health services research to leverage natural experiments and policy changes.