Methoden vergelijken

	Equivalentietest (TOST	Onafhankelijke t-toets voor twee steekproeven
Vakgebied	Statistiek	Statistiek
Familie	Hypothesis test	Hypothesis test
Jaar van ontstaan	1987	1908
Grondlegger	Donald J. Schuirmann	Student (W. S. Gosset)
Type	Parametric equivalence test	Parametric mean comparison
Oorspronkelijke bron	Schuirmann, D.J. (1987). A Comparison of the Two One-Sided Tests Procedure and the Power Approach for Assessing the Equivalence of Average Bioavailability. Journal of Pharmacokinetics and Biopharmaceutics, 15(6), 657–680.	Student (1908). The probable error of a mean. Biometrika, 6(1), 1–25.
Aliassen	TOST, two one-sided tests, bioequivalence test, Eşdeğerlik Testi (TOST — Two One-Sided Tests)	student t-test, two-sample t-test, unpaired t-test, bağımsız örneklem t-testi
Verwant	5	4
Samenvatting	The equivalence test using the Two One-Sided Tests (TOST) procedure is a parametric hypothesis test designed to demonstrate that the difference between two group means falls within a pre-specified equivalence region ±Δ. Introduced by Schuirmann (1987) in the context of pharmaceutical bioequivalence, TOST reverses the logic of classical null-hypothesis testing: instead of trying to detect a difference, it provides positive evidence of similarity.	The independent samples t-test is a parametric hypothesis test that compares the means of two independent groups to decide whether they differ significantly. It builds on the t-distribution introduced by Student (W. S. Gosset) in 1908 and assumes the measured values are continuous, approximately normally distributed, and have equal variances.