Methoden vergelijken

	AcroQoL: Acromegalie Kwaliteit van Leven Vragenlijst	ThyPRO: Thyroid-Related Patient Reported Outcomes Scale
Vakgebied	Endocrinologie	Endocrinologie
Familie	Process / pipeline	Process / pipeline
Jaar van ontstaan	2006	2009
Grondlegger	Markus Buchfelder, Dieter Weigel, Monica Droste, et al.	Torquil Watt, Jens Bjørner, Marianne Groenvold
Type	Patient self-report questionnaire	Patient self-report questionnaire
Oorspronkelijke bron	Buchfelder, M., Weigel, D., Droste, M., et al. (2006). The quality of life of acromegaly patients is markedly impaired: Data from the German Acromegaly Registry. Eur J Endocrinol, 150(4), 541-549.	Watt, T., Bjorner, J. B., Groenvold, M., et al. (2009). Establishing construct validity for the thyroid-related patient reported outcomes (ThyPRO): An initial examination. J Clin Endocrinol Metab, 94(9), 3572-3580.
Aliassen	Acromegaly QoL, Acro-QoL	ThyPRO-85, ThyPRO-39
Verwant	3	3
Samenvatting	AcroQoL is a disease-specific 22-item quality of life questionnaire developed to assess the multidimensional burden of acromegaly, a chronic growth hormone-secreting pituitary tumor disorder. Developed by Buchfelder and colleagues in 2006, it captures physical complications (joint/bone pain, carpal tunnel syndrome, metabolic disease), appearance-related concerns (facial changes, hand/foot enlargement), and psychological/social impacts (mood, social limitation, body image). It is the primary outcome measure for assessing quality of life in acromegaly treatment trials and clinical practice.	ThyPRO is a comprehensive patient-reported outcome measure assessing the quality of life impact of thyroid disease and its treatment across 13 dimensions. Developed by Watt and colleagues in 2009, it is the most extensively validated thyroid-specific instrument, covering both physical and psychological domains relevant to patients with hyperthyroidism, hypothyroidism, and thyroid cancer.