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UHDRS: Skala Penilaian Penyakit Huntington Bersepadu×MSFC: Multiple Sclerosis Functional Composite×
BidangNeurologiNeurologi
KeluargaProcess / pipelineProcess / pipeline
Tahun asal19961999
PengasasHuntington Study GroupGary Cutter, Richard Rudick, and NMSS Consortium
JenisClinician-rated and performance-basedClinician-administered performance test
Sumber perintisHuntington Study Group (1996). Unified Huntington's Disease Rating Scale: Reliability and consistency. Movement Disorders, 11(2), 136-142. link ↗Cutter, G. R., Baier, M. L., Rudick, R. A., et al. (1999). Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Multiple Sclerosis, 5(4), 244-250. DOI ↗
AliasUHDRS, Huntington's Rating ScaleMS Functional Composite
Berkaitan44
RingkasanThe Unified Huntington's Disease Rating Scale (UHDRS) is the comprehensive, multidomain assessment instrument for Huntington's disease, a neurodegenerative disorder caused by expanded CAG trinucleotide repeats. Developed by the Huntington Study Group in 1996, the UHDRS measures motor, cognitive, functional, and psychiatric manifestations of disease. The UHDRS is the gold-standard outcome measure in Huntington's disease clinical trials and longitudinal natural history studies.The Multiple Sclerosis Functional Composite (MSFC) is an objective, performance-based assessment of MS-related disability capturing three key functional domains: lower extremity mobility, upper extremity coordination, and cognitive/processing speed. Developed in 1999 by the National MS Society and adopted widely in clinical trials, the MSFC provides quantifiable endpoints complementing the Expanded Disability Status Scale (EDSS). The three-component design addresses EDSS limitations by including cognition and standardizing measurement via timed tasks.
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ScholarGateBandingkan kaedah: UHDRS · MSFC. Dicapai 2026-06-20 daripada https://scholargate.app/ms/compare