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Analisis Biomarker Air Liur×Indeks DMFT×
BidangPergigianPergigian
KeluargaProcess / pipelineProcess / pipeline
Tahun asal2000s+ (clinical application)1938
PengasasMultiple innovators (Giannobile, Malamud, et al.)Henry Klein, Cedric Palmer, and James Knutson
JenisLaboratory and point-of-care diagnosticsEpidemiological index
Sumber perintisGiannobile, W. V., McDevitt, J. T., Niedbala, R. S., Malamud, D., & Prozorovsky, T. (2009). Translating molecular diagnostics into clinical practice: Designing the next generation of oral health technologies. Advances in Dental Research, 23(1), 80-89. link ↗Klein, H., Palmer, C. E., & Knutson, J. W. (1938). Studies on dental caries: I. Dental status and dental needs of elementary school children. Public Health Reports, 53(32), 1259-1274. DOI ↗
Aliassaliva testing, salivary diagnostics, oral biomarker assessmentDMF index, DMF score, DMFT score
Berkaitan34
RingkasanSalivary biomarker analysis detects protein, molecular, or microbial markers in saliva that indicate oral and systemic disease. Salivary diagnostics assess risk and activity of dental caries, periodontal disease, oral cancer, and other conditions. Biomarkers include antimicrobial proteins (lysozyme, lactoferrin), inflammatory mediators (interleukins, TNF-alpha), cariogenic bacteria (Streptococcus mutans), and virulence factors. Point-of-care saliva testing offers rapid, non-invasive alternatives to conventional laboratory methods, enabling chairside diagnosis and personalized risk assessment.The DMFT (Decayed, Missing due to caries, Filled) Index is a standardized epidemiological measure of dental caries experience in permanent dentition. Developed by Klein, Palmer, and Knutson in 1938, it quantifies the number of permanent teeth that are decayed, missing due to caries, or filled due to caries. The DMFT Index remains the most widely used caries index globally, enabling comparison of oral health across populations and tracking disease burden over time.
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  1. v1
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ScholarGateBandingkan kaedah: Salivary Biomarker Analysis · DMFT Index. Dicapai 2026-06-19 daripada https://scholargate.app/ms/compare