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Regresi Bahaya Berkadaran Cox Multipusat×Analisis Kaplan-Meier×
BidangEpidemiologiEpidemiologi
KeluargaProcess / pipelineProcess / pipeline
Tahun asal1972 (Cox model); multicenter applications formalized 1980s–1990s1958
PengasasD. R. Cox (Cox PH model); multicenter extension developed through collaborative trial methodologyEdward L. Kaplan and Paul Meier
JenisSemi-parametric survival regression for clustered dataNonparametric survival estimator
Sumber perintisCox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society: Series B (Methodological), 34(2), 187–202. DOI ↗Kaplan, E. L., & Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗
Aliasmulticenter Cox regression, multisite Cox PH model, stratified Cox model across centers, multicenter survival regressionKM analysis, KM estimator, product-limit estimator, Kaplan-Meier curve
Berkaitan45
RingkasanMulticenter Cox proportional hazards regression extends the classic Cox PH model to studies conducted at two or more clinical sites or centers. It estimates the effect of predictors on time-to-event outcomes while explicitly accounting for clustering within centers, between-center heterogeneity, and potential differences in baseline hazard across sites. This design is standard practice in large multicenter RCTs and observational cohort studies in oncology, cardiology, and other clinical fields.Kaplan-Meier (KM) analysis is a nonparametric method for estimating the survival function from time-to-event data. Introduced by Kaplan and Meier in 1958, it produces the classic step-function survival curve that shows the probability of surviving beyond each observed event time, correctly accounting for censored observations — participants who left the study or had not yet experienced the event by the end of follow-up. It is one of the most widely used techniques in clinical and epidemiological research.
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ScholarGateBandingkan kaedah: Multicenter Cox proportional hazards · Kaplan-Meier Analysis. Dicapai 2026-06-19 daripada https://scholargate.app/ms/compare