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| Pengenalan Kumpulan Fungsian× | Perancangan Laluan Sintesis× | |
|---|---|---|
| Bidang | Kimia | Kimia |
| Keluarga | Process / pipeline | Process / pipeline |
| Tahun asal≠ | early 20th century | 1969 |
| Pengasas≠ | Organic chemistry community | Elias James Corey |
| Jenis≠ | Analytical methodology | Strategic planning methodology |
| Sumber perintis≠ | Clayden, J., Greeves, N., Warren, S., & Wothers, P. (2012). Organic Chemistry (2nd ed.). Oxford University Press. ISBN: 978-0199270293 | Corey, E. J., & Cheng, X. M. (1991). The Logic of Chemical Synthesis. John Wiley & Sons. ISBN: 978-0471096092 |
| Alias | functional group analysis, FG identification, structural analysis | retrosynthesis, retrosynthetic analysis, synthetic route design |
| Berkaitan | 3 | 3 |
| Ringkasan≠ | Functional group identification is the systematic determination of chemical functional groups present in organic molecules using spectroscopic, chemical, and structural data. Developed throughout the 20th century alongside spectroscopy and analytical chemistry, this methodology enables rapid structure elucidation by focusing on reactive moieties (alcohols, aldehydes, carboxylic acids, amines, etc.) rather than complete structure determination. | Synthesis route planning, grounded in retrosynthetic analysis, is a strategic approach to designing efficient chemical syntheses. Formalized by Elias James Corey in the 1960s (earning him the Nobel Prize in 1990), this methodology systematically deconstructs target molecules into simpler precursors and starting materials, enabling chemists to discover logical, economical, and practical synthesis routes. |
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