Catatan bukti metode

N-of-1 Trial

An N-of-1 trial is a single-patient randomized controlled trial in which a patient alternates between treatment A and treatment B (or active drug and placebo) in repeated, randomized cross-over periods. Developed systematically in the 1990s–2010s by Kravitz, Duan, and Vohra, N-of-1 trials enable personalized medicine by determining which treatment works best for that specific individual, avoiding the assumption that population-average effects apply to all patients. They are ideal for chronic conditions with variable outcomes and heterogeneous treatment response.

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Single-Patient N-of-1 Randomized Controlled Trial

Catatan metode taksonomi · process-pipeline / clinical-research

Buka metode lengkap

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Taxonomic bucketPragmatic Clinical Trialmachine-suggested · Relational suggestion, not evidence.See alsoRandomized Controlled Trialmachine-suggested · Relational suggestion, not evidence.Same method familyReal-World Evidence Studiesmachine-suggested · Relational suggestion, not evidence.