Quantitative Susceptibility Mapping
Quantitative Susceptibility Mapping (QSM) is a post-processing technique that converts MRI phase data into quantitative susceptibility values, enabling direct visualization and measurement of tissue magnetic properties. Developed by Wang, Liu, and colleagues, QSM transforms phase shifts caused by differences in magnetic susceptibility between tissues into tissue-specific biomarkers. It has revolutionized the sensitivity of MRI to iron, calcium, and other paramagnetic and diamagnetic substances, making it valuable in neurodegenerative disease diagnosis and tissue characterization.
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- Wang, Y., Liu, T. (2015). Quantitative susceptibility mapping (QSM): Decoding MRI data for a tissue magnetic biomarker. Magnetic Resonance in Medicine, 73(1), 82-101. · DOI 10.1002/mrm.25358
- Liu, T., Spincemaille, P., de Rochefort, L., et al. (2009). Calculation of susceptibility through multiple orientation sampling (COSMOS): a method for conditioning the inverse problem from undersample phase data. Magnetic Resonance in Medicine, 66(3), 579-592. · URL
- Haacke, E. M., Xu, Y., Cheng, Y. C., Reichenbach, J. R. (2004). Susceptibility weighted imaging (SWI). Magnetic Resonance in Medicine, 52(3), 612-618. · DOI 10.1002/mrm.20198
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