विधियों की तुलना करें
चुनी हुई विधियों की आमने-सामने समीक्षा करें; भिन्नता वाली पंक्तियाँ रेखांकित हैं।
| पृष्ठ प्लास्मोन अनुनाद× | परिपथी विवर्णता (Circular Dichroism)× | |
|---|---|---|
| क्षेत्र | स्पेक्ट्रोस्कोपी | स्पेक्ट्रोस्कोपी |
| परिवार | Process / pipeline | Process / pipeline |
| उद्भव वर्ष≠ | 1971 | 1969 |
| प्रवर्तक≠ | Erich Kretschmann | Jean-Claude Fasman |
| प्रकार≠ | Optical technique | Spectroscopic method |
| मौलिक स्रोत≠ | Kretschmann, E. (1971). Determination of optical constants of metals by excitation of surface plasmons. Zeitschrift für Physik, 241(4), 313-324. link ↗ | Greenfield, N. J., & Fasman, G. D. (1969). Computed circular dichroism spectra for protein secondary structures. Biochemistry, 8(10), 4108-4116. DOI ↗ |
| उपनाम | SPR, surface plasmon, SPR biosensing | CD spectroscopy, circular dichroism, CD analysis |
| संबंधित | 3 | 3 |
| सारांश≠ | Surface Plasmon Resonance (SPR) is a real-time, label-free technique for detecting and monitoring biomolecular interactions at a sensor surface by measuring changes in the refractive index caused by ligand binding. Developed by Kretschmann in 1971 and applied to biosensing by Liedberg, Nylander, and Lundström in 1983, SPR is now a gold standard for measuring binding kinetics (association and dissociation rates) and equilibrium binding constants in protein interactions, antibody-antigen recognition, and drug discovery. | Circular Dichroism (CD) spectroscopy measures the differential absorption of left- and right-circularly polarized light by optically active molecules, particularly proteins and nucleic acids. Introduced by Greenfield and Fasman in 1969, CD is a rapid, non-destructive technique for characterizing secondary structure (alpha-helix, beta-sheet), monitoring protein folding transitions, and assessing conformational changes in response to pH, temperature, or ligand binding. |
| ScholarGateडेटासेट ↗ |
|
|