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मिश्रण उपचार मॉडल×कैप्लान-मेयर सर्वाइवल एस्टिमेटर×
क्षेत्रउत्तरजीविताउत्तरजीविता
परिवारSurvival analysisSurvival analysis
उद्भव वर्ष19491958
प्रवर्तकBoag, J. W.Kaplan, E. L. & Meier, P.
प्रकारParametric mixture survival modelNon-parametric survival estimator
मौलिक स्रोतBoag, J. W. (1949). Maximum Likelihood Estimates of the Proportion of Patients Cured. Journal of the Royal Statistical Society B, 11(1), 15–53. link ↗Kaplan, E. L. & Meier, P. (1958). Nonparametric Estimation from Incomplete Observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗
उपनामcure fraction model, cure rate model, bounded cumulative hazard model, İyileşme Modeli (Mixture Cure Model)product-limit estimator, km curve, kaplan-meier sağkalım analizi
संबंधित22
सारांशThe mixture cure model, first proposed by Boag in 1949 for cancer survival data, is a parametric survival model that explicitly accounts for a fraction of subjects who will never experience the event of interest — the so-called cured or immune fraction. It is the appropriate tool whenever the Kaplan-Meier curve levels off into a long, stable plateau rather than continuing to decline, indicating that a proportion of subjects are permanently event-free.The Kaplan-Meier estimator, introduced by Kaplan and Meier in 1958, is a non-parametric method that estimates the survival curve — the probability of remaining event-free over time — from right-censored time-to-event data. The log-rank test is the companion procedure used to compare survival curves between groups.
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