विधियों की तुलना करें
चुनी हुई विधियों की आमने-सामने समीक्षा करें; भिन्नता वाली पंक्तियाँ रेखांकित हैं।
| अनुकूली यादृच्छिक नैदानिक परीक्षण× | यादृच्छिक नैदानिक परीक्षण (RCT)× | |
|---|---|---|
| क्षेत्र | महामारी विज्ञान | महामारी विज्ञान |
| परिवार | Process / pipeline | Process / pipeline |
| उद्भव वर्ष≠ | Late 1990s–2000s (widespread adoption post-2010) | 1948 (first rigorously conducted RCT — MRC streptomycin trial) |
| प्रवर्तक≠ | Donald Berry and colleagues; formalized by FDA guidance in 2010 and 2019 | Austin Bradford Hill; MRC Streptomycin Trial team |
| प्रकार≠ | Experimental clinical trial design | Interventional experimental study |
| मौलिक स्रोत≠ | Berry, D. A. (2006). Bayesian clinical trials. Nature Reviews Drug Discovery, 5(1), 27–36. DOI ↗ | Friedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2015). Fundamentals of Clinical Trials (5th ed.). Springer. ISBN: 978-3319185385 |
| उपनाम | adaptive RCT, adaptive trial design, response-adaptive randomization trial, adaptive clinical trial | RCT, randomized controlled trial, randomised controlled trial, clinical randomized trial |
| संबंधित | 6 | 6 |
| सारांश≠ | An adaptive randomized clinical trial (adaptive RCT) is a prospective experimental study that uses pre-specified rules to modify one or more trial aspects — such as sample size, allocation ratios, or treatment arms — based on accumulating data collected during the trial itself, while maintaining statistical validity and integrity of the study. | A randomized clinical trial (RCT) is an experimental study design in which participants are randomly assigned to an intervention group or a control group, then followed prospectively to compare outcomes. Random allocation is the defining feature: it distributes known and unknown confounders across groups by chance, making the RCT the strongest individual study design for establishing causal efficacy of a treatment or intervention under controlled conditions. |
| ScholarGateडेटासेट ↗ |
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