Machine Learning-Augmented Interrupted Time Series

Machine Learning-Augmented Interrupted Time Series (ML-ITS) estimates the causal effect of a discrete intervention by training a machine learning model on pre-intervention time series data, projecting a counterfactual trajectory into the post-intervention period, and measuring the gap between observed and predicted outcomes. It extends classical ITS by replacing parametric trend assumptions with flexible ML estimators such as gradient boosting, random forests, or Bayesian structural time-series models.