השוואת שיטות

	התגבשות מחדש	תכנון מסלול סינתזה
תחום	כימיה	כימיה
משפחה	Process / pipeline	Process / pipeline
שנת המקור	early 19th century	1969
הוגה השיטה	Organic chemistry tradition	Elias James Corey
סוג	Purification technique	Strategic planning methodology
מקור מכונן	Pavia, D. L., Lampman, G. M., Kriz, G. S., & Engel, R. G. (2014). A Small-Scale Approach to Organic Laboratory Techniques (4th ed.). Cengage Learning. ISBN: 978-1285749297	Corey, E. J., & Cheng, X. M. (1991). The Logic of Chemical Synthesis. John Wiley & Sons. ISBN: 978-0471096092
כינויים	crystallization purification, recrystallisation	retrosynthesis, retrosynthetic analysis, synthetic route design
קשורות	3	3
תקציר	Recrystallization is a classical purification technique in which a solid compound is dissolved in hot solvent, then allowed to crystallize upon cooling, yielding pure crystals while impurities remain in solution. Practiced for centuries in chemistry laboratories, recrystallization remains one of the most effective and accessible methods for purifying organic solids, especially when the target compound has low solubility at low temperatures.	Synthesis route planning, grounded in retrosynthetic analysis, is a strategic approach to designing efficient chemical syntheses. Formalized by Elias James Corey in the 1960s (earning him the Nobel Prize in 1990), this methodology systematically deconstructs target molecules into simpler precursors and starting materials, enabling chemists to discover logical, economical, and practical synthesis routes.