השוואת שיטות
סקרו את השיטות שבחרתם זו לצד זו; שורות שבהן יש הבדל מודגשות.
| ניסוי פיילוט מרובה זרועות× | ניסוי רב-זרועי אדפטיבי× | |
|---|---|---|
| תחום | תכנון ניסויים | תכנון ניסויים |
| משפחה | Process / pipeline | Process / pipeline |
| שנת המקור≠ | 1990s–2000s | 2000s–2010s (MAMS framework formalized c. 2003–2011) |
| הוגה השיטה≠ | Evolved from clinical trial methodology; consolidated in the 1990s–2000s | Patrick Royston, Mahesh Parmar, and colleagues (multi-arm multi-stage framework); further developed by James Wason, Thomas Jaki and others |
| סוג≠ | Experimental design (pilot/feasibility) | Experimental design |
| מקור מכונן≠ | Thabane, L., Ma, J., Chu, R., Cheng, J., Ismaila, A., Rios, L. P., Robson, R., Thabane, M., Giangregorio, L., & Goldsmith, C. H. (2010). A tutorial on pilot studies: The what, why and how. BMC Medical Research Methodology, 10(1), 1. DOI ↗ | Royston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256. DOI ↗ |
| כינויים | pilot multi-arm trial, feasibility multi-arm study, pilot parallel-arm experiment, preliminary multi-arm experiment | MAMS design, multi-arm adaptive trial, adaptive platform trial, response-adaptive multi-arm experiment |
| קשורות≠ | 6 | 3 |
| תקציר≠ | A pilot multi-arm experiment is a small-scale preliminary trial that tests the feasibility, logistics, and parameter estimates needed to plan a full-scale multi-arm study. It simultaneously evaluates two or more active treatment arms alongside a control, providing early evidence on recruitment rates, retention, protocol adherence, variability, and likely effect sizes before committing to a resource-intensive definitive experiment. | An adaptive multi-arm experiment simultaneously evaluates several treatment conditions against a common control and modifies the trial in real time based on accumulating data — dropping ineffective arms early, reallocating participants toward promising ones, or adjusting sample sizes — all while controlling error rates. The approach maximizes information gained per participant and reduces the time and cost required to identify effective treatments relative to running sequential separate trials. |
| ScholarGateמערך נתונים ↗ |
|
|