השוואת שיטות

	ניתוח מטה-אנליטי של תגובה-למינון	ניתוח מטא-אנליזה רשתי
תחום	אפידמיולוגיה	סינתזת ראיות
משפחה	Process / pipeline	Process / pipeline
שנת המקור	1992	2002
הוגה השיטה	Sander Greenland & Matthew P. Longnecker	Lumley (2002)
סוג	Quantitative meta-analytic method	Method
מקור מכונן	Greenland, S., & Longnecker, M. P. (1992). Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. American Journal of Epidemiology, 135(11), 1301–1309.	Lumley, T. (2002). Network meta-analysis for indirect treatment comparisons. Statistics in Medicine, 21(16), 2313–2324.
כינויים	dose-response meta-analysis, DRMA, pooled dose-response modeling, trend meta-analysis	Mixed Treatment Comparison, MTC, Indirect Comparison Meta-Analysis
קשורות	2	1
תקציר	Meta-analytic dose-response analysis pools summary statistics from multiple epidemiological studies to characterize how disease risk changes across ordered levels of an exposure. Rather than comparing a single high-exposure group against a reference, it reconstructs a continuous or categorical exposure-risk curve across the full range of doses, providing far richer evidence about the shape and magnitude of an association than any single study can supply.	Network meta-analysis (NMA) is a systematic method for comparing multiple interventions simultaneously within a single analytical framework, incorporating both direct evidence (head-to-head trials) and indirect evidence (comparisons via common comparators). First formalized by Lumley in 2002, NMA allows researchers to rank treatments and quantify comparative effectiveness even when some treatment pairs have never been directly studied.